01 - Pat the brisket dry and evenly season all sides with kosher salt, black pepper, smoked paprika, thyme, and oregano.
02 - Heat olive oil in a large skillet over medium-high heat and sear the brisket for 3 to 4 minutes on each side until well browned.
03 - Place the seared brisket into a slow cooker.
04 - Arrange onions, carrots, celery, and minced garlic around and on top of the brisket.
05 - Whisk together beef broth, red wine if using, tomato paste, and Worcestershire sauce in a bowl, then pour evenly over the brisket and vegetables.
06 - Cover and cook on low heat for 8 hours until the brisket is fork-tender.
07 - Remove brisket from the cooker and let rest for 10 minutes before slicing against the grain.
08 - Skim excess fat from the cooking liquid, then serve slices with the vegetables and spoon the sauce over the top.